Publications in TaejoonLab

2024

  1. Jeong J#, Kwon K#, Geisseova TK, Lee J, Kwon T*, Lim C*. () Drosulfakinin signaling encodes early-life memory for adaptive social plasticity. , eLife., 13:e103973. PMID:39692597 doi:10.7554/eLife.103973.
  2. Kim S#, Hyun H#, Im JK, Lee MS, Koh H, Kang D, Nho SH, Kang JH*, Kwon T*, Kim H*. () Fast and accurate multi-bacterial identification using cleavable and FRET-based peptide nucleic acid probes. , Biosens Bioelectron., 271:116950. PMID:39631211 doi:10.1016/j.bios.2024.116950.
  3. Kim Y, Lee HK, Park KY, Ismail T, Lee H, Ryu HY, Cho DH, Kwon TK, Park TJ, Kwon T, Lee HS. () Actin depolymerizing factor destrin governs cell migration in neural development during Xenopus embryogenesis. , Mol Cells., 47(6):100076. PMID:38825188 doi:10.1016/j.mocell.2024.100076.
  4. Choi JW#, Kim K#, Mukhambetiyar K, Lee NK, Sabaté Del Río J, Joo J, Park CG, Kwon T*, Park TE. () Organ-on-a-Chip Approach for Accelerating Blood-Brain Barrier Nanoshuttle Discovery. , ACS Nano., 18(22):14388-14402. PMID:38775287 doi:10.1021/acsnano.4c00994.
  5. Hong J, Kwon KY, Jang DG, Kwon T, Yoon H, Park TJ. () Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage. , Biomed Pharmacother., 174:116434. PMID:38513592 doi:10.1016/j.biopha.2024.116434.
  6. Bredeson JV, Mudd AB, Medina-Ruiz S, Mitros T, Smith OK, Miller KE, Lyons JB, Batra SS, Park J, Berkoff KC, Plott C, Grimwood J, Schmutz J, Aguirre-Figueroa G, Khokha MK, Lane M, Philipp I, Laslo M, Hanken J, Kerdivel G, Buisine N, Sachs LM, Buchholz DR, Kwon T, Smith-Parker H, Gridi-Papp M, Ryan MJ, Denton RD, Malone JH, Wallingford JB, Straight AF, Heald R, Hockemeyer D, Harland RM, Rokhsar DS. () Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. , Nat Commun., 15(1):579. PMID:38233380 doi:10.1038/s41467-023-43012-9.

2023

  1. Ismail T, Lee H, Kim Y, Ryu HY, Cho DH, Ryoo ZY, Lee DS, Kwon TK, Park TJ, Kwon T, Lee HS. (2023) PCNB exposure during early embryogenic development induces developmental delay and teratogenicity by altering the gene expression in Xenopus laevis. , Environ Toxicol., 38(1):216-224 PMID:3.6218123e+07 doi:10.1002/tox.23679
  2. Ismail T, Lee HK, Lee H, Kim Y, Kim E, Lee JY, Kim KB, Ryu HY, Cho DH, Kwon TK, Park TJ, Kwon T, Lee HS. (2023) Early life exposure to perfluorooctanesulfonate (PFOS) impacts vital biological processes in Xenopus laevis: Integrated morphometric and transcriptomic analyses. , Ecotoxicol Environ Saf., 269:115820. PMID:3.8103469e+07 doi:10.1016/j.ecoenv.2023.115820.
  3. Chae S#, Park TJ, Kwon T*. (2023) Convergent differentiation of multiciliated cells. , Sci Rep., 13(1):23028. PMID:38155158 doi:10.1038/s41598-023-50077-5.
  4. Jeong H#, Moon HE, Yun S, Cho SW, Park HR, Park SH, Myung K, Kwon T*, Paek SH*. (2023) Enrichment of Deleterious Mutated Genes Involved in Ciliary Function and Histone Modification in Brain Cancer Patient-Derived Xenograft Models. , Biomedicines., 11(11):2934. PMID:38001935 doi:10.3390/biomedicines11112934.
  5. Lee YJ, Shin KJ, Jang HJ, Ryu JS, Lee CY, Yoon JH, Seo JK, Park S, Lee S, Je AR, Huh YH, Kong SY, Kwon T, Suh PG, Chae YC. (2023) GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis. , Dev Cell., 58(4):320-334.e8. PMID:36800996 doi:10.1016/j.devcel.2023.01.006.
  6. Kwon KY, Jeong H#, Jang DG, Kwon T*, Park TJ. (2023) Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia. , Genes Genomics., 45(2):157-167. PMID:36508087 doi:10.1007/s13258-022-01350-w.
  7. Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN. (2023) A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. , Sci Adv., 9(14):eadd5745. PMID:37027470 doi:10.1126/sciadv.add5745.

2022

  1. Jeong H#, Wie M#, Baek IJ, Sohn G, Um SH, Lee SG, Seo Y, Ra J, Lee EA, Kim S, Kim BG, Deshpande RA, Paull TT, Han JS, Kwon T*, Myung K*. (2022) TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11. , Cells, 11(24):4095 PMID:36552858 doi:10.3390/cells11244095
  2. Hwang H, Yun S, Arcanjo RB, Divyanshi, Chen S, Mei W, Nowak RA, Kwon T*, Yang J*. (2022) Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER. , Cell Rep. 2022 Dec 13;, 41(11):111802 PMID:36516762 doi:10.1016/j.celrep.2022.111802.
  3. Kwon KY#, Jeong H#, Jang DG, Kwon T*, Park TJ*. (2022) Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia. , Genes Genomics., Epub ahead of print. PMID:3.6508087e+07 doi:10.1007/s13258-022-01350-w.
  4. Jang DG, Kwon KY, Kweon YC, Kim BG, Myung K, Lee HS, Park CY, Kwon T, Park TJ* (2022) GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base , eLife, 11:e81016 PMID:36004726 doi:10.7554/eLife.81016
  5. Kwon K#, Cho H#, Lee S, Cho EJ, Yu W, Kok CYL, Je HS, Kim JI, Cho HJ*, Kwon T** (2022) Adaptive cellular response of the substantia nigra dopaminergic neurons upon age-dependent iron accumulation , Aging Cell, 21(9):e13694 PMID:35984750 doi:10.1111/acel.13694
  6. Kwon T#*, Ra JS#, Lee S#, Baek I-J#, Khim KW, Lee EA, Song EK, Otarbayev D, Jung W, Park YH, Wie M, Bae J, Cheng H, Park JH, Kim N, Seo Y, Yun S, Kim HE, Moon HE, Paek SH, Park TJ, Park YU, Rhee H, Choi JH, Cho SW*, Myung K* (2022) Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9 , Proc Natl Acad Sci USA, 19(9):e2103532119 PMID:35217600 doi:10.1073/pnas.2103532119
  7. Lee MS#, Hyun H#, Park I#, Kim S#, Jang D-H, Kim S, Im J-K, Kim H*, Lee JH*, Kwon T*, and Kang JH* (2022) Quantitative fluorescence in situ hybridization (FISH) of magnetically confined bacteria enables early detection of human bacteremia , Small Methods, e2101239 PMID:35112812 doi:10.1002/smtd.202101239
  8. Sim HJ, Cho C, Kim HE, Hong JY, Song EK, Kwon KY, Jang DG, Kim SJ, Lee HS, Lee C, Kwon T, Yang S*, Park TJ* (2022) Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance , Sci Adv., 8(3):eabl4222 PMID:35061535 doi:10.1126/sciadv.abl4222

2021

  1. Lee H, Lee NY, Kim Y, Choi HS, Ismail T, Ryu HY, Cho DH, Ryoo ZY, Lee DS, Kwon TK, Park TJ, Kwon T*, Lee HS* (2021) Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development , Antioxidants, 10(10):1636 PMID:34679770 doi:10.3390/antiox10101636
  2. Hyun H#, Lee MS#, Park I#, Ko HS, Yun S, Jang DH, Kim S, Kim H, Kang JH*, Lee JH*, Kwon T** (2021) Analysis of Porcine Model of Fecal-Induced Peritonitis Reveals the Tropism of Blood Microbiome , Front. Cell. Infect. Microbiol., 11:676650 PMID:34527598 doi:10.3389/fcimb.2021.676650
  3. Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB (2021) A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone , Dev. Dyn., 250(5):717-731 PMID:33368695 doi:10.1002/dvdy.289

2020

  1. Jang DG, Sim HJ, Song EK, Kwon T, Park TJ (2020) Extracellular matrixes and neuroinflammation , BMB Rep., 53(10):491-499. PMID:32731916 doi:10.5483/BMBRep.2020.53.10.156
  2. Lee H, Ismail T, Kim Y, Chae S, Ryu HY, Lee DS, Kwon TK, Park TJ, Kwon T*, Lee HS* (2020) Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis , Antioxidants, 9(12):E1265 PMID:33322741 doi:10.3390/antiox9121265
  3. Lee BE, Kim HY, Kim H-J, Jung H, Kim B-G, Lee H-E, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, My ung K, Suh P-G, Kwon T, Kim J-I* (2020) O-GlcNAcylation regulates dopamine neuron function, survival, and degeneration in Parkinson disease , Brain, 143(12):3699-3716 PMID:33300544 doi:10.1093/brain/awaa320
  4. Borzée A, Messenger KR, Chae S, Andersen D, Groffen J, Kim YI, An J, Othman SN, Ri K, Nam TY, Bae Y, Ren J-L, Li J-T, Chuang M-F, Yi Y, Shin Y, Kwon T, Jang Y, Min M-S (2020) Yellow sea mediated segregation between North East Asian Dryophytes species , PLoS ONE, 15(6):e0234299 PMID:32579561 doi:10.1371/journal.pone.0234299
  5. Yang HS#, Sim HJ#, Cho H, Bang WY, Kim HE, Kwon TK, Kwon T*, Park TJ* (2020) Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells , Sci Rep., 10(1):6224 PMID:32277121 doi:10.1038/s41598-020-63085-6
  6. McWhite CD, Papoulas O, Drew K, Cox RM, June V, Dong OX, Kwon T, Wan C, Salmi ML, Roux SJ, Browning KS, Chen ZJ, Ronald PC, Marcotte EM (2020) A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies, Cell, 181(2):460-474 PMID:32191846 doi:10.1016/j.cell.2020.02.049
  7. Sim HJ#, Yun S#, Kim HE, Kwon KY, Kim GH, Yun S, Kim BG, Myung K, Park TJ*, Kwon T* (2020) Simple Method To Characterize the Ciliary Proteome of Multiciliated Cells, J Proteome Res., 19(1):391-400 PMID:31689115 doi:10.1021/acs.jproteome.9b00589

2019

  1. Mitros T, Lyons JB, Session AM, Jenkins J, Shu S, Kwon T, Lane M, Ng C, Grammer TC, Khokha MK, Grimwood J, Schmutz J, Harland RM, Rokhsar DS (2019) A chromosome-scale genome assembly and dense genetic map for Xenopus tropicalis , Dev. Biol., PMID:30980799 doi:10.1016/j.ydbio.2019.03.015
  2. Kim B, Fukuda M, Lee JY, Su D, Sanu S, Silvin A, Khoo ATT, Kwon T, Liu X, Chi W, Liu X, Choi S, Wan DSY, Park SJ, Kim JS, Ginhoux F, Je HS, Chang YT (2019) Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate , Angew. Chem., PMID:31038839 doi:10.1002/anie.201903058
  3. Ji Y, Chae S, Lee HK, Park I, Kim C, Ismail T, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Moon PG, Baek MC, Park MJ, Kil IS, Rhee SG, Kim J, Huh YH, Shin JY, Min KJ, Kwon TK, Jang DG, Woo HA, Kwon T, Park TJ, Lee HS (2019) Peroxiredoxin5 controls vertebrate ciliogenesis by modulating mitochondrial ROS , Antioxid. Redox Signal., PMID:30191719 doi:10.1089/ars.2018.7507
  4. Yu W, Yen YC, Lee YH, Tan S, Xiao Y, Lokman H, Ting AKT, Ganegala H, Kwon T, Ho WK, Je HS (2019) Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice , Mol. Brain, PMID:30935412 doi:10.1186/s13041-019-0452-5
  5. Lee HK, Ismail T, Kim C, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Kwon T, Park TJ, Lee HS (2019) Lysine demethylase 3a in craniofacial and neural development during Xenopus embryogenesis , Int J Mol Med., PMID:30569092 doi:10.3892/ijmm.2018.4024

2018

  1. Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T*, Lee HS* (2018) Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development , Epigenetics Chromatin, PMID:30522514 doi:10.1186/s13072-018-0241-x
  2. Gibeaux R, Miller K, Acker R, Kwon T, Heald R (2018) Xenopus Hybrids Provide Insight Into Cell and Organism Size Control , Front Physiol., PMID:30564147 doi:10.3389/fphys.2018.01758
  3. Song EK, Jeon J, Jang DG, Kim HE, Sim HJ, Kwon KY, Medina-Ruiz S, Jang HJ, Lee AR, Rho JG, Lee HS, Kim SJ, Park CY, Myung K, Kim W, Kwon T, Yang S, Park TJ (2018) ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis , Sci Transl Med., PMID:30305454 doi:10.1126/scitranslmed.aam7486
  4. Ismail T, Lee HK, Kim C, Kwon T, Park TJ, Lee HS (2018) KDM1A microenvironment, its oncogenic potential, and therapeutic significance, Epigenetics Chromatin., PMID:29921310 doi:10.1186/s13072-018-0203-3
  5. Sim HJ, Kim SH, Myung KJ, Kwon T, Lee HS, Park TJ (2018) Xenopus: An alternative model system for identifying muco-active agents , PLoS ONE, PMID:29470529 doi:10.1371/journal.pone.019331
  6. Gibeaux R, Acker R, Kitaoka M, Georgiou G, van Kruijsbergen I, Ford B, Marcotte EM, Nomura DK, Kwon T, Veenstra GJC, Heald R (2018) Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus , Nature, PMID:29320479 doi:10.1038/nature25188

2017

  1. Chae S, Lee HK, Kim YK, Sim HJ, Ji Y, Kim C, Ismail T, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Min KJ, Kwon TK, Park MJ, Han JK, Kwon T, Park TJ, Lee HS (2017) Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels , Sci Rep., PMID:28827763 doi:10.1038/s41598-017-09262-6
  2. Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C (2017) Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing , Dev. Biol., PMID:27209239 doi:10.1016/j.ydbio.2016.05.014
  3. Lee SY, Kang MG, Shin S, Kwak C, Kwon T, Seo JK*, Kim JS*, Rhee HW* (2017) Architecture Mapping of the Inner Mitochondrial Membrane Proteome by Chemical Tools in Live Cells , J Am Chem Soc., 139(10):3651-3662 PMID:28156110 doi:10.1021/jacs.6b10418
  4. Kwon T#* (2017) AmphiBase: A new genomic resource for non-model amphibian species, Genesis, 55:e23010 PMID:28095648 doi:10.1002/dvg.23010

2016

  1. Session AM#, Uno Y#, Kwon T#, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen S, Quigley IK, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortiede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra G, Fujiyama A, Harland RM, Taira M, Rokhsar DS (2016) Genome evolution in the allotetraploid frog Xenopus laevis , Nature, 538(7625), 336-343 PMID:27762356 doi:10.1038/nature19840
  2. LEE S-Y, Lee H, Lee H-K, Lee S-W, Ha SC, Kwon T, Seo JK, Lee C, Rhee H-W (2016) Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells , ACS Central Sci., 2(8):506–516 PMID:27610411 doi:10.1021/acscentsci.6b00137

2015

  1. Kwon T#* (2015) Benchmarking transcriptome quantification methods for duplicated genes in Xenopus laevis , Cytogenet. and Genome Res., 145(3-4):253-64 PMID:26112470 doi:10.1159/000431386